Stephen J Freedland Selected Research

Prostate-Specific Antigen (Semenogelase)

12/2021	A phase 3 randomised study of enzalutamide plus leuprolide and enzalutamide monotherapy in high-risk non-metastatic hormone-sensitive prostate cancer with rising PSA after local therapy: EMBARK study design.
3/2021	Chronic Baseline Prostate Inflammation is Associated with Lower Tumor Grade in Men with Prostate Cancer on Repeat Biopsy: Results from the REDUCE Study.
1/2021	Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer.
1/2021	Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia.
1/2021	Medication patterns of abiraterone acetate plus prednisone or enzalutamide and PSA progression in veterans with metastatic castration-resistant prostate cancer.
12/2020	Predictors of survival, healthcare resource utilization, and healthcare costs in veterans with non-metastatic castration-resistant prostate cancer.
11/2020	Asian Race and Risk of Prostate Cancer: Results from the REDUCE Study.
10/2020	Obese men undergoing radical prostatectomy: Is robotic or retropubic better to limit positive surgical margins? Results from SEARCH.
9/2020	Competing Risks of Mortality among Men with Biochemical Recurrence after Radical Prostatectomy.
3/2020	Diagnostic Properties of Total and Free Prostate-Specific Antigen to Predict Overall and Clinically Significant Prostate Cancer Among Men With Low Testosterone and Prior Negative Biopsy.

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Stephen J Freedland Research Topics

Disease

318	Prostatic Neoplasms (Prostate Cancer) 12/2022 - 04/2003
128	Neoplasms (Cancer) 06/2022 - 02/2002
60	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2007
41	Obesity 10/2020 - 01/2004
26	Margins of Excision 10/2020 - 02/2002
17	Disease Progression 12/2022 - 07/2009
14	Inflammation (Inflammations) 12/2022 - 06/2009
11	Extranodal Extension 10/2020 - 06/2003
10	Weight Loss (Weight Reduction) 12/2022 - 01/2009
10	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 10/2017
8	Lower Urinary Tract Symptoms 02/2022 - 11/2016
7	Adenocarcinoma 01/2022 - 11/2007
6	Cardiovascular Diseases (Cardiovascular Disease) 04/2022 - 01/2010
6	Pain (Aches) 01/2022 - 03/2002
6	Lymphatic Metastasis 01/2022 - 06/2003
6	Insulin Resistance 12/2021 - 01/2004
5	Carcinoma (Carcinomatosis) 01/2020 - 12/2003
5	Body Weight (Weight, Body) 01/2019 - 07/2010
4	Erectile Dysfunction 01/2022 - 04/2012
4	Hypertension (High Blood Pressure) 12/2021 - 04/2012
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2021 - 04/2012
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2021 - 11/2016
3	Hypercholesterolemia 01/2020 - 04/2012
2	Renal Cell Carcinoma (Grawitz Tumor) 03/2022 - 01/2003
2	Fatigue 01/2022 - 01/2021
2	Abdominal Obesity 12/2021 - 11/2014
2	Nocturia 06/2021 - 01/2019
2	Spontaneous Fractures (Pathological Fracture) 01/2020 - 11/2019
2	Spinal Cord Compression 01/2020 - 11/2019
2	Melanoma (Melanoma, Malignant) 12/2019 - 01/2013
2	7 Hereditary Prostate Cancer 01/2019 - 10/2005
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019 - 11/2015
2	Hypoxia (Hypoxemia) 05/2018 - 02/2010

Drug/Important Bio-Agent (IBA)

128	Prostate-Specific Antigen (Semenogelase)IBA 12/2021 - 02/2002
46	AndrogensIBA 01/2022 - 04/2003
35	Dutasteride (Avodart)FDA Link 02/2022 - 01/2011
22	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2009
21	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2022 - 05/2008
21	CholesterolIBA 04/2022 - 05/2008
16	CarbohydratesIBA 12/2022 - 07/2006
13	Hormones (Hormone)IBA 12/2021 - 04/2003
12	Biological ProductsIBA 12/2020 - 02/2005
11	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 07/2009
10	Testosterone (Sustanon)FDA Link 01/2022 - 02/2006
9	LipidsIBA 04/2022 - 09/2010
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2006
7	Insulin (Novolin)FDA Link 05/2013 - 01/2004
6	Triglycerides (Triacylglycerol)IBA 04/2022 - 11/2014
6	HDL LipoproteinsIBA 01/2020 - 11/2014
5	enzalutamideIBA 01/2022 - 01/2021
5	Docetaxel (Taxotere)FDA Link 01/2022 - 02/2014
5	Phosphotransferases (Kinase)IBA 01/2022 - 10/2013
4	Immune Checkpoint InhibitorsIBA 03/2022 - 01/2019
4	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2012
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 12/2018
4	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 03/2016
4	oxidized low density lipoproteinIBA 01/2018 - 11/2014
4	AntigensIBA 08/2017 - 11/2011
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2015 - 04/2012
4	Dietary Fats (Dietary Fat)IBA 07/2013 - 02/2004
4	AdiponectinIBA 05/2013 - 10/2005
4	LeptinIBA 05/2013 - 01/2004
4	Insulin-Like PeptidesIBA 05/2013 - 01/2004
4	Insulin-Like Growth Factor I (IGF-1)IBA 12/2011 - 08/2007
3	C-Reactive ProteinIBA 12/2022 - 06/2009
3	abirateroneIBA 01/2022 - 12/2020
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2021 - 01/2010
3	Uridine Diphosphate (UDP)IBA 01/2021 - 01/2013
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 08/2006
3	Phenobarbital (Luminal)FDA Link 01/2021 - 01/2016
3	CalciumIBA 01/2019 - 01/2012
3	Messenger RNA (mRNA)IBA 05/2018 - 08/2006
3	Pharmaceutical PreparationsIBA 02/2017 - 03/2010
3	Agent OrangeIBA 07/2015 - 05/2009
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 12/2011 - 08/2006
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2011 - 08/2006
2	Narcotics (Narcotic Analgesics)IBA 01/2022 - 03/2002
2	sipuleucel-T (APC8015)FDA Link 10/2021 - 01/2020
2	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 11/2015
2	27-hydroxycholesterolIBA 01/2020 - 01/2017
2	MagnesiumIBA 01/2019 - 10/2013

Therapy/Procedure

136	Prostatectomy (Retropubic Prostatectomy) 06/2022 - 02/2002
78	Therapeutics 03/2022 - 06/2003
64	Castration 01/2022 - 02/2004
36	Radiotherapy 01/2022 - 06/2003
10	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 12/2022 - 05/2009
9	Drug Therapy (Chemotherapy) 01/2022 - 01/2005
9	Chemoprevention 06/2021 - 05/2008
8	Cystectomy 01/2022 - 02/2013
7	Fat-Restricted Diet (Diet, Fat Restricted) 12/2011 - 02/2004
6	Immunotherapy 03/2022 - 01/2019
4	Glycemic Control 01/2022 - 10/2010
4	Salvage Therapy 01/2019 - 07/2005
4	Hemodilution 01/2017 - 11/2007
4	Ketogenic Diet 10/2012 - 07/2006
4	Nephrectomy 09/2011 - 03/2002
2	Treatment Delay 01/2022 - 08/2013
2	Precision Medicine 12/2020 - 01/2017
2	Cryosurgery 11/2018 - 12/2013
2	Aftercare (After-Treatment) 01/2018 - 03/2011